TY - CHAP M1 - Book, Section TI - Cardiovascular Drugs A1 - Leikin, Scott M. A1 - Leikin, Jerrold B. A2 - Tenenbein, Milton A2 - Macias, Charles G. A2 - Sharieff, Ghazala Q. A2 - Yamamoto, Loren G. A2 - Schafermeyer, Robert PY - 2019 T2 - Strange and Schafermeyer's Pediatric Emergency Medicine, 5e AB - β-Blocker and calcium channel blocker poisoning have significant morbidity, and their hallmark is bradycardia and hypotension.If standard Pediatric Advance Life Support (PALS) protocols do not restore adequate cardiovascular function, stepwise administration of glucagon, hyperinsulinemia-euglycemia (HIE) therapy, and lipid emulsion should be considered.Administration of specific anti-digoxin Fab antibody fragments is a highly effective treatment for digoxin poisoning.Consider naloxone if PALS protocols fail to reverse clonidine toxicity. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1155748818 ER -