TY - CHAP M1 - Book, Section TI - Alexander Disease (AD) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - A degenerative disorder of the nervous system caused by leukodystrophy. Affects mostly males and usually begins at approximately 6 months of age. Symptoms include mental and physical retardation, enlargement of the brain and head, seizures, and spasticity in arms and legs. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164061262 ER -