TY - CHAP M1 - Book, Section TI - Kabuki Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is a congenital syndrome characterized by multiple congenital anomalies, typical facial features (regardless of ethnic origin), and mild-to-moderate mental retardation. Children with Kabuki Syndrome have a distinctive facial appearance characterized by micrognathia, blue sclerae, ptosis, strabismus, cleft lips and palate, palpebral fissures, everted lower eyelids, prominent eyelashes, arched eyebrows, a broad nose with a flattened or depressed tip, and large, misshaped ears. These facial features develop over several years. Other features include skeletal abnormalities that include brachydactyly, clinodactyly, flat feet, scoliosis, or kyphosis. Significant cardiac malformations have been reported. Anesthesiologists should be aware of the possibility of an unexpected difficult airway management, respiratory problems, neurological and musculoskeletal disorders, and latex allergy when managing anesthesia for a patient with Kabuki Syndrome SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/04 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164074573 ER -