TY - CHAP M1 - Book, Section TI - Leber Hereditary Optic Neuropathy (LHON) A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is a rare hereditary form of optic atrophy that usually affects young males. Characterized by sudden bilateral cloudiness of vision, followed by scotoma, rapid deterioration of central vision, and occasional color vision disorders. Associated with atrophy of the optic nerve fibers and retinae. Considered a mitochondrial disease. Cardiac conduction defects have been reported with this condition. Blindness is usually seen before the age of 40 years. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164076458 ER -