TY - CHAP M1 - Book, Section TI - Lennox-Gastaut Syndrome A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is a severe childhood onset form of intractable epilepsy that begins between the second and sixth year of life. Classically, it is defined by a triad of clinical signs consisting of severe learning disabilities, frequent seizure activities, and an EEG recording characterized by less than 2.5 Hz slow pike wave recording. Daily multiple seizures are typical and the most frequent type of seizures is myotonic and occurring 90% during the night. The second most frequent presentation is myoclonic seizures triggered when the patient is physically exhausted. It is associated with a poor prognosis in childhood. Five percent of patients die within 10 years from the onset of the disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164076600 ER -