TY - CHAP M1 - Book, Section TI - Myasthenia Gravis A1 - Bissonnette, Bruno A1 - Luginbuehl, Igor A1 - Engelhardt, Thomas PY - 2019 T2 - Syndromes: Rapid Recognition and Perioperative Implications, 2e AB - It is a neuromuscular disorder characterized by significant muscle weakness and rapid muscle fatigue during mild exercise, such as a slow walk. Congenital myasthenias are present in the first years of childhood. Spontaneous forms of Myastheria Gravis (MS) are usually recognized during adulthood. Usually apparent during adulthood, the onset of the symptoms occurs at any age and spontaneously. Most individuals present eyelid ptosis, diplopia, and excessive muscle fatigue following exercise. Other clinical features commonly include dysarthria, dysphagia, and proximal limb weakness. Approximately 10% may develop potentially life-threatening complications as a consequence of severe respiratory depression (myasthenic crisis). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/09 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1164079718 ER -