TY  - CHAP
M1  - Book, Section
TI  - Meconium Aspiration
A1  - Gomella, Tricia Lacy
A1  - Eyal, Fabien G.
A1  - Bany-Mohammed, Fayez
PY  - 2020
T2  - Gomella's Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 8e
AB  - Meconium  is  the  first  intestinal  discharge  of  the  newborn  infant.  In  addition  to  epithelial  cells,  fetal  hair,  mucus,  and  bile,  meconium  also  contains  a  number  of  proinflammatory  components.  With  the  passage  of  meconium  in  utero,  the  meconium-stained  amniotic  fluid  (MSAF)  may  be  aspirated.  The  presence  of  MSAF  in  the  trachea  can  cause  airway  obstruction.  With  aspiration  below  the  vocal  cords,  further  obstruction,  air  trapping,  and  an  inflammatory  response  can  result  in  severe  respiratory  distress.  Hallmarks  include  early  onset  of  respiratory  distress  in  an  infant  with  MSAF  who  presents  with  poor  lung  compliance,  hypoxemia,  and  a  characteristic  lung  radiograph.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1168357955
ER  -