TY - CHAP M1 - Book, Section TI - Spontaneous Intestinal Perforation A1 - Gomella, Tricia Lacy A1 - Eyal, Fabien G. A1 - Bany-Mohammed, Fayez PY - 2020 T2 - Gomella's Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 8e AB - A spontaneous intestinal perforation (SIP) is a single intestinal perforation typically involving the antimesenteric border of distal ileum and usually occurs in extremely premature infants in the first 1 to 2 weeks of life. These infants, typically, have not been fed (or have received minimum feeds). If laparotomy is performed, a focal hemorrhagic necrosis with well-defined margins is observed, in contrast to ischemic and coagulative necrosis seen in necrotizing enterocolitis (NEC). The bowel proximal and distal to the perforation appears normal. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1168358311 ER -