TY - CHAP M1 - Book, Section TI - Fetal Neurosurgery A1 - Rosner, Mara A1 - Baschat, Ahmet A1 - Groves, Mari A1 - S. Faden, Majed A1 - Laurie, Melissa A1 - Miller, Jena A2 - Malinger, Gustavo A2 - Monteagudo, Ana A2 - Pilu, Gianluigi A2 - Paladini, Dario A2 - Timor-Tritsch, Ilan E. PY - 2023 T2 - Timor's Ultrasonography of the Prenatal Brain, 4e AB - KEY POINTSFetal myelomeningocele (MMC) repair reduces the need for postnatal ventriculoperitoneal shunting at 1 year by at least a half compared with postnatal repair.Motor and bladder function outcome studies after fetal MMC repair are encouraging, and further study is underway.Preliminary findings demonstrate that fetoscopic MMC repair seems to offer similar neonatal benefits to the open approach, with the advantage of allowing for safe vaginal delivery in the index and future pregnancies. Fetoscopic MMC repair is not associated with an increased risk for uterine rupture, compared to an 11% risk after open repair.In 1986, a moratorium was placed on human fetal ventriculoperitoneal shunting. However, due to improvements in fetal diagnosis and intervention techniques that may translate to improved case selection and outcomes, there is renewed interest in further investigation of this treatment approach. SN - PB - McGraw Hill Education CY - New York, NY Y2 - 2024/04/18 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1194721711 ER -