TY - CHAP M1 - Book, Section TI - Chapter 193. Anaphylaxis, Urticaria, and Angioedema A1 - Riedel, Marc A. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Anaphylaxis, urticaria, and angioedema frequently share a common pathophysiology in that these conditions most commonly result from IgE-mediated mast cell activation resulting in the release of histamine, leukotrienes, and other mast cell mediators. Urticaria and angioedema are isolated to mucocutaneous symptoms whereas anaphylaxis is an acute systemic reaction that may rapidly lead to cardiopulmonary collapse. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/29 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7018636 ER -