TY  - CHAP
M1  - Book, Section
TI  - Chapter 209. Autoinflammatory Disorders
A1  - Hashkes, Philip J.
A2  - Rudolph, Colin D.
A2  - Rudolph, Abraham M.
A2  - Lister, George E.
A2  - First, Lewis R.
A2  - Gershon, Anne A.
PY  - 2011
T2  - Rudolph's Pediatrics, 22e
AB  - Autoinflammatory  syndromes,  formerly  known  as  periodic  fever  syndromes,  are  defined  as  recurrent  attacks  of  often  unprovoked  systemic  inflammation  that  are  related  to  a  lack  of  adequate  regulation  of  the  innate  immune  system.1-3  Unlike  autoimmune  diseases,  these  conditions  are  not  generally  marked  by  autoantibodies  or  autoreactive  T  cells.  Many  of  these  syndromes  have  a  genetic  etiology3,4  (eTable  209.1)  involving  the  excessive  production  and  activity  of  interleukin  (IL)-1β.5  The  conditions  are  no  longer  known  as  periodic  fever  syndromes,  6-8  because  most  are  not  truly  periodic  nor  is  fever  a  necessary  feature.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/18
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=7019999
ER  -