TY - CHAP M1 - Book, Section TI - Chapter 266. Listeriosis A1 - Shehab, Ziad M. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Listeria monocytogenes is a food-borne pathogen that causes disease primarily in neonates, pregnant women, the elderly, and the immunocompromised host.1 It is worldwide in distribution and is acquired relatively frequently in developed countries due to consumption of refrigerated, contaminated, ready-to-eat food, mostly dairy products and cold cuts.2 Listeriosis is a zoonosis of many animal species. In humans, it causes epidemic and sometimes sporadic outbreaks of febrile gastroenteritis.3 Systemic infection results from passage of the organism across the intestinal mucosal barrier by endocytosis, coupled with its ability to evade immune surveillance by cell-to-cell spread; deficiencies in T-cell immunity such as in pregnancy and immunosuppression increase the risk of listeriosis.4,5 Extraintestinal disease results from hematogenous dissemination with particular predilection for central nervous system and placental infections. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7026002 ER -