TY - CHAP M1 - Book, Section TI - Chapter 330. Strongyloidiasis A1 - Oberhelman, Richard A. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Strongyloidiasis is an intestinal parasitic infection caused by the roundworm Strongyloides stercoralis. Strongyloides has a unique ability to replicate within its host and behave as a potentially fatal opportunistic pathogen in patients who are immunocompromised, particularly in those receiving corticosteroids. The global prevalence of strongyloidiasis is estimated to be 30 to 100 million cases.1Strongyloides infections are endemic in most tropical regions of the world, with hyperendemic areas in Brazil and central Africa. Endemic foci are also found in certain temperate areas such as the south-central United States (especially eastern Kentucky and rural Tennessee) and both western and eastern Europe. Most infections diagnosed in temperate climates were acquired by travel in the tropics. Humans are the principal host, but dogs, cats, and other animals may be reservoirs.2 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7031113 ER -