TY - CHAP M1 - Book, Section TI - Chapter 407. Motor Disorders of the Stomach, Small Bowel, and Colon A1 - Sood, Manu R. A1 - Calkins, Casey M. A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - Propulsion of the luminal contents along the gastrointestinal tract requires coordinated contractions of the intestinal smooth muscle in response to input from the enteric neurons. The enteric nervous system is capable of independent function that is modulated by motor input from the brain. Gastrointestinal motor function develops between 26 to 36 weeks of gestation, but it is poorly developed before 30 weeks and not fully developed until 36 weeks gestation. Thus, it is not unusual for preterm infants to have poor gastric emptying and feeding intolerance.1 GI motility disorders result from weak or uncoordinated contractions due to abnormalities of the neuromuscular apparatus or abnormal sensory and motor input from the brain. These disorders range in severity from mild disorders, such as recurrent abdominal pain, to severe, such as chronic idiopathic pseudo-obstruction syndrome with intestinal failure.2 SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7036950 ER -