TY - CHAP M1 - Book, Section TI - Chapter 409. Inflammatory Disorders of the Stomach A1 - Dohil, Ranjan A1 - Hassall, Eric A2 - Rudolph, Colin D. A2 - Rudolph, Abraham M. A2 - Lister, George E. A2 - First, Lewis R. A2 - Gershon, Anne A. PY - 2011 T2 - Rudolph's Pediatrics, 22e AB - The terms acid peptic diseases, peptic diseases, or acid-related disorders are used synonymously to describe conditions that involve gastric acid and pepsin in their pathogenesis; they refer to a number of disorders including esophagitis, gastritis, peptic ulcer disease, and duodenitis. Gastritis is a condition diagnosed histologically, not clinically or radiologically.1-5 It is characterized by the presence of inflammatory cells and is often found to be present in biopsies taken from gastric mucosa that appears normal at endoscopy. Some forms of chronic, severe gastritis may destroy mucosal elements, resulting in atrophic gastritis and intestinal metaplasia, which in some forms may be preneoplastic. Although gastritis and ulcer disease may occur as stand-alone entities, they are often part of a continuum of disease.2,3,6 A special case is that of Helicobacter pylori, an important cause of gastritis and peptic ulcer disease discussed separately. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/11/02 UR - accesspediatrics.mhmedical.com/content.aspx?aid=7037392 ER -