TY  - CHAP
M1  - Book, Section
TI  - Chapter 472. Glomerular Diseases
A1  - Eddy, Allison A.
A2  - Rudolph, Colin D.
A2  - Rudolph, Abraham M.
A2  - Lister, George E.
A2  - First, Lewis R.
A2  - Gershon, Anne A.
PY  - 2011
T2  - Rudolph's Pediatrics, 22e
AB  - Glomerular  diseases  present  clinically  in  several  different  ways,  depending  on  the  nature  and  severity  of  the  primary  disease  and  the  extent  to  which  the  normal  physiological  functions  of  the  glomerulus  are  perturbed.1,2  Some  children  with  glomerulonephritis  (GN)  are  found  incidentally  to  have  microscopic  hematuria  or  proteinuria  when  checked  by  routine  urinalysis  but  are  otherwise  asymptomatic.  At  the  other  extreme,  children  may  become  critically  ill  with  oligoanuric  rapidly  progressive  GN  in  need  of  urgent  dialysis.  A  few  glomerular  diseases  are  inherited  (see  Chapter  473),  but  most  forms  of  GN  are  acquired  and  are  generally  considered  to  be  immunologically  mediated.  There  are  three  classical  clinical  syndromes  that  develop  from  glomerular  injury:  acute  and  chronic  glomerulonephritis,  defined  by  the  triad  of  hematuria,  hypertension,  and  azotemia;  nephrotic  syndrome,  defined  by  proteinuria  and  hypoalbuminemia;  and  hemolytic  uremic  syndrome,  defined  by  microangiopathic  hemolytic  anemia,  thrombocytopenia,  and  renal  insufficiency.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/18
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=7045367
ER  -