TY - CHAP M1 - Book, Section TI - Renal Developmental Physiology and Pediatric Fluid and Electrolyte Management A1 - Keckler, Scott J. A1 - Tuggle, David W. A2 - Ziegler, Moritz M. A2 - Azizkhan, Richard G. A2 - Allmen, Daniel von A2 - Weber, Thomas R. PY - 2014 T2 - Operative Pediatric Surgery, 2e AB - Fetal urine production begins at 10 to 13 weeks gestation, and although urine production increases thereafter throughout pregnancy, glomerular filtration rate (GFR) is always lower in preterm infants.Renal function changes quickly in the fetus and newborn with an increasing GFR and tubular maturity leading to enhanced concentrating ability.Calculation of maintenance fluid requirements is size dependent; however, practically, calculations are more typically based on body weight rather than body surface area.Premature infant fluid requirements are different from term infant requirements in both total fluid volumes and electrolyte content.To avoid serious neurologic injury, sodium abnormalities should not be corrected quickly. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/12 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1100430928 ER -