TY - CHAP M1 - Book, Section TI - Persistent Pulmonary Hypertension of the Newborn A1 - Gomella, Tricia Lacy A1 - Cunningham, M. Douglas A1 - Eyal, Fabien G. A1 - Tuttle, Deborah J. PY - 2013 T2 - Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e AB - Persistent pulmonary hypertension of the newborn (PPHN) is a condition characterized by marked pulmonary hypertension resulting from elevated pulmonary vascular resistance (PVR) and altered pulmonary vasoreactivity, leading to right-to-left extrapulmonary shunting of blood across the foramen ovale and the ductus arteriosus, if it is patent. It is associated with a wide array of cardiopulmonary disorders that may also cause intrapulmonary shunting. When this disorder is of unknown cause and is the primary cause of cardiopulmonary distress, it is often called “idiopathic PPHN” or persistent fetal circulation. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1107524834 ER -