TY - CHAP M1 - Book, Section TI - Lupus—Systemic and Cutaneous A1 - Raman, Vidya A1 - Mayeaux, E.J. A2 - Usatine, Richard P. A2 - Sabella, Camille A2 - Smith, Mindy Ann A2 - Mayeaux, E.J. A2 - Chumley, Heidi S. A2 - Appachi, Elumalai PY - 2015 T2 - The Color Atlas of Pediatrics AB - A previously healthy 16-year-old African American girl presented to the clinic with alopecia and rash over her face and arms for 6 months (Figures 173-1 and 173-2). She reported pain in her knees and ankles for a year and an oral ulcer 3 months ago, which had healed. Laboratory evaluation was remarkable for a low white blood cell count at 2.4 × 1000/uL (normal 5.0–13.0 × 100/uL), hemoglobin of 10.8 g/dL (normal 11.8–16.0 g/dL), and platelet count of 109 × 1000/uL (normal 142–424 × 1000/uL). Erythrocyte sedimentation rate was elevated at 45 mm/hr (normal 0–15 mm/hr). Antinuclear antibody was positive at 1:640 with a strongly positive antidouble stranded DNA antibody confirming a diagnosis of systemic lupus erythematosus (SLE). Urinalysis did not show proteinuria to suggest renal involvement. She was treated with prednisone and hydroxychloroquine resulting in improvement in her problems. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1114878164 ER -