TY - CHAP M1 - Book, Section TI - Chronic Granulomatous Disease A1 - Greiwe, Justin A1 - Dückers, Gregor A1 - Niehues, Tim A1 - Schroer, Brian A2 - Usatine, Richard P. A2 - Sabella, Camille A2 - Smith, Mindy Ann A2 - Mayeaux, E.J. A2 - Chumley, Heidi S. A2 - Appachi, Elumalai PY - 2015 T2 - The Color Atlas of Pediatrics AB - A 4-year-old boy presents with a recent history of persistent pneumonia. A detailed past medical history reveals several recurrent infections including pneumonia and lymph node abscesses growing Staphylococcus aureus and Burkholderia cepacia. His parents claim that he has been prescribed multiple courses of antibiotics over the last month with no improvement in his respiratory symptoms. There is no family history of immunodeficiency. Examination of the child revealed mild subcostal retractions and diffuse rales bilaterally. A chest x-ray demonstrated bilateral infiltrates of the upper and middle lung fields and a CT showed multifocal pneumonia (Figure 220-1). Diagnostic bronchoalveolar lavage and serological tests confirmed the presence of invasive pulmonary aspergillosis and the patient was placed on appropriate antifungal treatment. Because of the history and types of infection, a work-up for immunodeficiency was undertaken and the child was found to have chronic granulomatous disease. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/09 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1114880569 ER -