TY - CHAP M1 - Book, Section TI - The Female Genital System A1 - Wells, Robert G. PY - 2015 T2 - Diagnostic Imaging of Infants and Children AB - The Müllerian (paramesonephric) ducts develop at 5 to 6 weeks gestational age in conjunction with the Wolffian (mesonephric) ducts. In the absence of "testis-determining factor" of the Y chromosome, the Wolffian ducts degenerate. At 7 to 9 weeks gestational age, the Müllerian ducts fuse at the midline to form the uterovaginal canal. The proximal segments of the uterovaginal canal are derived from coelomic epithelium; these remain unfused and give rise to the fallopian tubes. At approximately 8 weeks gestational age, the uterovaginal canal extends inferiorly to reach the urogenital sinus (vertical fusion). At the same time, the vaginal plate develops in the distal portion of the uterovaginal canal. The vaginal plate subsequently undergoes canalization. Approximately the upper two-thirds of the vagina derive from the Müllerian ducts and the lower one-third develops from the urogenital sinus. The uterus has assumed its mature configuration by 12 weeks gestational age. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - accesspediatrics.mhmedical.com/content.aspx?aid=1148951975 ER -