TY  - CHAP
M1  - Book, Section
TI  - Common Chromosomal Trisomies 21, 18, and 13
A1  - Wilnai, Yael
A1  - Manning, Melanie
A2  - Stevenson, David K.
A2  - Cohen, Ronald S.
A2  - Sunshine, Philip
PY  - 2015
T2  - Neonatology: Clinical Practice and Procedures
AB  - Chromosome  abnormalities  account  for  a  significant  portion  of  genetic  disease  and  are  important  causes  of  congenital  malformations  and  pregnancy  loss.  Cytogenetic  disorders  are  found  in  nearly  1%  of  live  births;  thus,  performing  a  karyotype  on  a  newborn  with  multiple  congenital  anomalies  can  provide  valuable  information  with  respect  to  management  questions  and  prognosis  counseling.  Chromosome  analysis  is  indicated  as  a  diagnostic  procedure  in  a  number  of  different  general  clinical  situations,  such  as  problems  with  early  growth,  development,  stillbirth,  and  neonatal  death.  For  infants  in  the  neonatal  period,  performing  a  chromosome  analysis  may  be  considered  if  any  of  the  following  features  are  demonstrated:  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspediatrics.mhmedical.com/content.aspx?aid=1109799398
ER  -