RT Book, Section
A1 Kessler, Sudha K.
A1 Dlugos, Dennis J.
A2 Duchowny, Michael
A2 Cross, J. Helen
A2 Arzimanoglou, Alexis
SR Print(0)
ID 1138409836
T1 Generalized Seizures in Early Childhood (2–4 Years of Age)
T2 Pediatric Epilepsy
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071496216
LK accesspediatrics.mhmedical.com/content.aspx?aid=1138409836
RD 2024/04/20
AB As  discussed  in  Chapter  1,  classification  of  epileptic  seizure  types  has  practical  importance  but  also  significant  limitations.  Historically  used  terms  may  not  accurately  reflect  the  complex  pathophysiology  or  phenomenology  of  seizures.  Generalized  seizures  involve  synchronous  epileptic  discharges  throughout  the  cerebral  cortex,  and  are  further  distinguished  by  the  terms  primary  or  secondarily.  Seizures  that  appear  to  have  synchronous  bihemispheric  involvement  at  initiation  (based  on  clinical  and  electrographic  evidence)  are  primary  generalized  seizures  and  those  that  begin  in  a  focal  area  of  cortex  and  subsequently  spread  to  involve  both  hemispheres  are  secondarily  generalized.  This  distinction  is  not  always  straightforward,  and  a  high  index  of  suspicion  should  be  maintained  for  focal  onset  seizures  that  appear  generalized,  because  evaluation  and  treatment  differs  between  generalized  and  focal  epilepsies.