RT Book, Section
A1 Cross, J. Helen
A2 Duchowny, Michael
A2 Cross, J. Helen
A2 Arzimanoglou, Alexis
SR Print(0)
ID 1138410269
T1 Focal Seizures in Early Childhood
T2 Pediatric Epilepsy
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071496216
LK accesspediatrics.mhmedical.com/content.aspx?aid=1138410269
RD 2024/04/19
AB Several  studies  have  demonstrated  that  seizure  manifestations  evolve  according  to  developmental  age.  Although  myelination  is  largely  complete  by  two  years  of  age,  clinical  seizure  manifestations  continue  to  evolve  beyond  this  age  (probably  reflecting  the  caudorostral  pattern  of  brain  development),  with  an  adult  pattern  of  semiology  unlikely  before  age  6  years.  A  high  index  of  suspicion  is  therefore  required  when  evaluating  the  clinical  description  of  events  for  focality.  The  assessment  will  have  obvious  management  implications,  particularly  for  the  diagnosis  of  an  epilepsy  syndrome.  Most  studies  evaluating  seizure  semiology  have  been  performed  in  surgical  cohorts,  where  documentation  of  seizure  type  is  made  with  video  EEG  telemetry  and  confirmed  by  seizure  freedom  after  removal  of  the  suspect  area.