RT Book, Section A1 Nabulsi, Mona A1 Mikati, Mohamad A. A2 Duchowny, Michael A2 Cross, J. Helen A2 Arzimanoglou, Alexis SR Print(0) ID 1138412201 T1 Clinical Trials Versus Anecdotal Reports T2 Pediatric Epilepsy YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071496216 LK accesspediatrics.mhmedical.com/content.aspx?aid=1138412201 RD 2024/03/29 AB The choice of antiepileptic drugs (AEDs) entails a number of considerations detailed later. All these considerations cannot be fully or adequately addressed by controlled studies alone, and are thus grounds for individualization of therapy. Although evidence-based data from randomized controlled trials (RCTs) on drug efficacy are a critical part of the choice, as they provide an objective method to compare efficacy, they often do not address many other aspects that are important in such choices such as comparative efficacy, comorbidity, and ease of use.