RT Book, Section A1 Gaily, Eija A1 Lindhout, Dick A2 Duchowny, Michael A2 Cross, J. Helen A2 Arzimanoglou, Alexis SR Print(0) ID 1138412327 T1 Teratogenicity of Antiepileptic Drugs T2 Pediatric Epilepsy YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071496216 LK accesspediatrics.mhmedical.com/content.aspx?aid=1138412327 RD 2024/03/28 AB In most women with epilepsy, it is necessary to continue antiepileptic drug (AED) treatment during pregnancy to reduce the risks caused by epileptic seizures for both mother and child.1,2,3 The risk of maternal death during pregnancy has been estimated to be ten times higher in women with epilepsy compared to the general population,4 possibly due to poor compliance with AED treatment and seizure occurrence. Seizure-related accidents and convulsive status epilepticus during pregnancy are associated with an increased risk of fetal death.5 Even brief generalized tonic–clonic seizures during pregnancy may have an unfavorable effect on cognitive outcome based on retrospective data,4 although this has not been confirmed prospectively.6,7