RT Book, Section
A1 Fukao, Toshiyuki
A1 Harding, Cary O.
A2 Sarafoglou, Kyriakie
A2 Hoffmann, Georg F.
A2 Roth, Karl S.
SR Print(0)
ID 1140315552
T1 Ketone Synthesis and Utilization Defects
T2 Pediatric Endocrinology and Inborn Errors of Metabolism, 2e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071773140
LK accesspediatrics.mhmedical.com/content.aspx?aid=1140315552
RD 2024/10/05
AB The  ketone  bodies  acetoacetate  (AcAc)  and  3-hydroxybutyrate  (3HB)  are  four  carbon  carboxylic  acids  produced  in  the  liver,  mainly  from  the  oxidation  of  fatty  acids.  Ketone  bodies  are  transported  from  the  liver  to  other  tissues,  where  they  can  be  reconverted  to  acetyl-CoA  to  produce  energy,  via  the  citric  acid  cycle.  3-Hydroxybutyrate,  acetoacetate,  and  acetone  are  all  colloquially  called  ketone  bodies,  but  chemically  3-hydroxybutyrate  is  a  carboxylic  acid,  not  a  ketone  body.