RT Book, Section
A1 Bronicki, Ronald A.
A1 Price, Jack
A2 Kline, Mark W.
SR Print(0)
ID 1182926062
T1 Cardiogenic Shock
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182926062
RD 2024/09/13
AB The  clinical  syndrome  of  shock  has  great  potential  for  significant  morbidity  and  mortality  and  is  one  of  the  most  challenging  conditions  to  treat.  In  accordance  with  Barcroft’s  original  construct  for  conceptualizing  shock  that  was  published  nearly  100  years  ago,  shock  results  from  1  or  more  of  the  following  mechanisms:  impaired  oxygenation  or  hypoxic  hypoxia,  reduced  oxygen  carrying  capacity  or  anemic  hypoxia,  limited  cardiac  output  or  stagnant  hypoxia,  or  impaired  oxygen  utilization  or  histotoxic  hypoxia  (eg,  cyanide  toxicity).  Shock  results  from  inadequate  oxygen  delivery  relative  to  oxygen  demand,  and  if  the  body’s  intrinsic  compensatory  mechanisms  of  increased  cardiac  output  and  oxygen  extraction  are  insufficient,  or  left  inadequately  treated,  this  can  rapidly  result  in  organ  dysfunction  or  failure.  The  etiologies  of  shock  are  broad,  as  are  its  manifestations,  and  in  this  review  we  will  discuss  the  pathophysiology,  assessment,  and  treatment  of  cardiogenic  shock.