RT Book, Section A1 Bostwick, Bret L. A1 Bacino, Carlos A. A2 Kline, Mark W. SR Print(0) ID 1182930808 T1 Birth Defects, Malformations, and Syndromes T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182930808 RD 2024/04/20 AB Birth defects are relatively common, with major anomalies occurring in approximately 3% to 4% of live births. More than 20% of infant deaths in the United States are directly attributable to birth defects. In addition to mortality, birth defects also cause long-term morbidity, including intellectual disability and physical dysfunction, that can limit the productivity of individuals. These long-term disabilities can have significant impact on individuals, families, healthcare systems, and communities.