RT Book, Section A1 Letra, Ariadne A1 Chiquet,, Brett A1 Streff, Haley A2 Kline, Mark W. SR Print(0) ID 1182931258 T1 Cleft Lip and Palate T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182931258 RD 2024/03/29 AB Oral-facial clefts, including cleft lip and/or cleft palate, are the most common craniofacial birth defects, affecting approximately 135,000 newborns worldwide each year. The costs of caring for a child with an oral-facial cleft are more than $100,000 and creates significant financial and healthcare burdens for these families. Infants born with an oral-facial cleft may have feeding, swallowing, breathing, speech, and hearing complications. Therefore, a multidisciplinary team, including surgical, dental, speech, genetic, and nutrition experts, is typically involved in patient care. This chapter will discuss the pathogenesis, epidemiology, clinical manifestations, diagnosis, treatment, and prevention of oral-facial clefts.