RT Book, Section
A1 Leung, Daniel
A1 Pavia, Andrew T.
A2 Kline, Mark W.
SR Print(0)
ID 1182936639
T1 Salmonella, Shigella, and Escherichia coli
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182936639
RD 2024/04/18
AB The  family  Enterobacteriaceae  is  a  large,  heterogeneous  group  of  gram-negative  bacteria.  Many  are  normal  inhabitants  of  the  gastrointestinal  tract  of  humans  and  other  animals,  but  members  also  frequently  cause  disease  in  human  beings.  Among  the  Enterobacteriaceae,  Salmonella,  Shigella,  Yersinia,  and  a  number  of  specific  phenotypes  of  Escherichia  coli  are  important  causes  of  gastroenteritis.  In  addition  to  diarrhea,  these  organisms  cause  a  variety  of  extraintestinal  infections.  Each  genera  includes  a  heterogenous  group  of  organisms  that  vary  in  their  epidemiology  and  clinical  characteristics.  Enterobacteriaceae  possess  3  major  antigenic  groups  that  react  with  antisera:  (1)  the  O  or  somatic  antigens;  (2)  the  H  or  flagellar  antigens;  and  (3)  the  K  or  capsular  antigens.  Serotyping  has  historically  been  an  important  means  of  subtyping  these  enteric  pathogens;  this  technique  is  being  partially  superseded  by  our  increasing  ability  to  identify  genotypic  and  phenotypic  markers  of  virulence.