RT Book, Section A1 Hay, Jr, William W. A1 Levin, Myron J. A1 Deterding, Robin R. A1 Abzug, Mark J. SR Print(0) ID 1145454558 T1 Cholestasis, Extrahepatic: Choledochal Cyst T2 Quick Medical Diagnosis & Treatment Pediatrics YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781264257614 LK accesspediatrics.mhmedical.com/content.aspx?aid=1145454558 RD 2024/04/25 AB Extrahepatic neonatal cholestasis is characterized byComplete and persistent cholestasis (acholic stools) in the first 3 months of lifeLack of patency of the extrahepatic biliary tree proved by intraoperative, percutaneous, or endoscopic cholangiographyFirm to hard hepatomegalyTypical features on histologic examination of liver biopsy tissueCause only 2–5% of cases of extrahepatic neonatal cholestasis; incidence is higher in girls and patients of Asian descentIn most cases, the clinical manifestations, basic laboratory findings, and histopathologic features on liver biopsy are indistinguishable from those associated with biliary atresia