RT Book, Section A1 Hay, Jr, William W. A1 Levin, Myron J. A1 Deterding, Robin R. A1 Abzug, Mark J. SR Print(0) ID 1145458196 T1 Pulmonary Hypoplasia T2 Quick Medical Diagnosis & Treatment Pediatrics YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781264257614 LK accesspediatrics.mhmedical.com/content.aspx?aid=1145458196 RD 2023/04/02 AB Defined as incomplete development of one or both lungsCharacterized by a reduction in alveolar number and a reduction in airway branchesPresent in up to 10–15% of perinatal autopsiesCongenital diaphragmatic hernia is the most common cause, with an incidence of 1:2200 birthsCan be a result ofAn intrathoracic mass, resulting in lack of space for the lungs to growDecreased size of the thoraxDecreased fetal breathing movementsDecreased blood flow to the lungsPrimary mesodermal defect affecting multiple organ systemsOther causes includeExtralobar sequestrationDiaphragmatic eventration or hypoplasiaThoracic neuroblastomaFetal hydropsFetal hydrochylothoraxChest cage abnormalities, diaphragmatic elevation, oligohydramnios, chromosomal abnormalities, severe musculoskeletal disorders, and cardiac lesions may also result in hypoplastic lungs