RT Book, Section A1 Hay, Jr, William W. A1 Levin, Myron J. A1 Deterding, Robin R. A1 Abzug, Mark J. SR Print(0) ID 1145459239 T1 Trisomy 18 Syndrome T2 Quick Medical Diagnosis & Treatment Pediatrics YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781264257614 LK accesspediatrics.mhmedical.com/content.aspx?aid=1145459239 RD 2024/10/05 AB Incidence is about 1:4000 live birthsRatio of affected males to females is approximately 1:3Characterized byPrenatal and postnatal growth retardation, which is often severeHypertonicityComplications are related to associated anomaliesDeath is often caused by heart failure or pneumonia and usually occurs in infancy or early childhoodSmall percentage reach adulthood; usually show significant cognitive disabilitiesA support group for families is called SOFT (see http://www.trisomy.org/)