RT Book, Section
A1 Chinen, Javier
A2 Kline, Mark W.
SR Print(0)
ID 1182931536
T1 Increased Susceptibility to Infections
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182931536
RD 2024/04/23
AB Many  children  are  evaluated  by  their  physicians  because  of  recurrent  infections,  a  relatively  common  complaint  in  early  childhood.  These  children  are  considered  to  have  an  increased  susceptibility  to  infections  as  compared  with  children  of  similar  age.  Both  extrinsic  and  host  factors  can  increase  the  risk  of  developing  infections,  and  may  be  found  in  most  such  cases  (Table  183-1).  Identification  and  management  of  these  underlying  conditions  would  result  in  a  reduction  in  frequency  of  infectons.  Examples  of  extrinsic  factors  include  human  immunodeficiency  virus  infection,  use  of  immunosuppressor  drugs,  high  exposure  to  infectious  agents  in  a  daycare  setting,  presence  of  foreign  bodies,  or  exposure  to  parental  smoking.  Host  factors  that  increase  risks  of  developing  infections  include  genetic  deficiencies  of  the  immune  response  and  several  other  conditions:  respiratory  allergies,  abnormal  anatomy,  and  diseases  affecting  barriers  or  epithelia  such  as  cystic  fibrosis.