RT Book, Section A1 Hron, Jonathan D. A2 Zaoutis, Lisa B. A2 Chiang, Vincent W. SR Print(0) ID 1146113432 T1 Cyanosis T2 Comprehensive Pediatric Hospital Medicine, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071829281 LK accesspediatrics.mhmedical.com/content.aspx?aid=1146113432 RD 2024/04/20 AB Cyanosis is a bluish discoloration of the skin, mucous membranes, tongue, lips, or nail beds and is due to an increased concentration of reduced hemoglobin (Hb) in the circulation.1 Clinically evident cyanosis typically occurs at an oxygen saturation of 85% or less.2 It is easier to identify under natural lighting and is typically more difficult to detect in patients with mild cyanosis, dark skin pigmentation, or anemia. Long-term complications of chronic cyanosis include clubbing, polycythemia, stroke, brain abscess, platelet abnormalities, lower-than-expected IQ, scoliosis, and hyperuricemia.1