RT Book, Section A1 Parker, Sarah E.S. A1 Rehm, Kris P. A2 Zaoutis, Lisa B. A2 Chiang, Vincent W. SR Print(0) ID 1146113545 T1 Fever T2 Comprehensive Pediatric Hospital Medicine, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071829281 LK accesspediatrics.mhmedical.com/content.aspx?aid=1146113545 RD 2024/03/28 AB Most children undergo at least one medical evaluation for a febrile illness before their third birthday, and nearly one third of pediatric outpatient visits are for fever. Fever is an increase in body temperature, usually by 1°C to 4°C, that is regulated by the central nervous system and mediated by endocrine, autonomic, and behavioral mechanisms. Although fever is a common manifestation of infection, it is a symptom of many diseases, both infectious and noninfectious.1-3