RT Book, Section A1 McCulloh, Russell A1 Thomson, Joanna A2 Zaoutis, Lisa B. A2 Chiang, Vincent W. SR Print(0) ID 1146119413 T1 Device-Related Infections T2 Comprehensive Pediatric Hospital Medicine, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071829281 LK accesspediatrics.mhmedical.com/content.aspx?aid=1146119413 RD 2024/03/29 AB Invasive medical devices are commonly used in hospitalized children. They result in more than 250,000 infections each year in the United States.1 A catheter-related bloodstream infection (CRBSI) is defined as bacteremia or fungemia in a patient with an intravascular catheter that is the presumed source of infection. This definition belies the challenges a clinician faces in accurately diagnosing CRBSI in children, including difficulties in diagnostic testing and variability in epidemiology based on age, intravascular device used, infusate being given, and underlying clinical condition.2 Additionally, central venous catheters (CVCs) pose other infectious complications aside from CRBSI, including local infection at exit sites, and they can become secondarily infected through seeding of bacteria due to bacteremia originating from infection at a distant site.