RT Book, Section
A1 Downes, Kevin J.
A1 Danziger-Isakov, Lara A.
A2 Zaoutis, Lisa B.
A2 Chiang, Vincent W.
SR Print(0)
ID 1146119624
T1 Infections in Special Hosts
T2 Comprehensive Pediatric Hospital Medicine, 2e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071829281
LK accesspediatrics.mhmedical.com/content.aspx?aid=1146119624
RD 2024/09/20
AB The  definition  of  immune  compromise  is  characterized  by  an  impairment  of  a  host’s  ability  to  effectively  handle  infectious  challenges.  As  new  therapeutic  options  for  previously  untreatable  illnesses  become  available,  a  growing  number  of  children  fall  into  this  category.  This  chapter  focuses  primarily  on  the  infection-related  issues  among  children  who  are  immunocompromised  owing  to  solid  organ  or  hematopoietic  cell  transplantation;  splenic  dysfunction  will  also  be  addressed.  These  special  hosts  may  present  for  the  evaluation  of  unexplained  fever,  or  with  focal  signs  of  infection,  and  often  require  a  different  approach  than  pursued  in  an  otherwise  healthy  child.  The  goal  of  this  chapter  is  to  provide  the  pediatric  hospitalist  with  a  framework  for  infectious  diseases  evaluation  in  these  children.  Infectious  complications  related  to  chemotherapy  for  malignancy  are  discussed  in  Chapter  133.