RT Book, Section
A1 Lo, Mindy S.
A2 Zaoutis, Lisa B.
A2 Chiang, Vincent W.
SR Print(0)
ID 1146122655
T1 Systemic Lupus Erythematosus
T2 Comprehensive Pediatric Hospital Medicine, 2e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071829281
LK accesspediatrics.mhmedical.com/content.aspx?aid=1146122655
RD 2024/04/19
AB Systemic  lupus  erythematosus  (SLE)  is  a  chronic,  potentially  serious  systemic  autoimmune  disease.  It  is  characterized  biochemically  by  the  presence  of  autoantibodies;  in  particular,  antibodies  directed  against  nuclear  antigens.  SLE  is  a  heterogeneous  disease  in  that  clinical  manifestations  can  vary  significantly  from  patient  to  patient,  ranging  from  mild  presentations  to  severe  organ  dysfunction.  Morbidity  and  mortality  rates  have  improved  dramatically  over  the  past  few  decades  due  to  advances  in  therapy.