RT Book, Section A1 Nigrovic, Lise E. A1 Burns, Michele M. A2 Zaoutis, Lisa B. A2 Chiang, Vincent W. SR Print(0) ID 1146124070 T1 Heat Disorders T2 Comprehensive Pediatric Hospital Medicine, 2e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9780071829281 LK accesspediatrics.mhmedical.com/content.aspx?aid=1146124070 RD 2024/04/24 AB Heat disorders such as heat exhaustion and heatstroke result from a failure of the body’s regulatory mechanisms to maintain a constant body temperature. Individuals at the extremes of age and those with chronic diseases are the most vulnerable. Approximately 400 people die annually in the United States from heat-related illness.1 Fever, on the other hand, is an elevation in body temperature secondary to mediators of inflammation and involves an adjustment in the physiologic set point (see Chapter 24). Malignant hyperthermia, another thermoregulatory disorder, results from a triggering exposure in a genetically susceptible individual.