RT Book, Section
A1 Riedl, Marc A.
A2 Kline, Mark W.
SR Print(0)
ID 1182931856
T1 Anaphylaxis, Urticaria, and Angioedema
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182931856
RD 2024/04/23
AB Anaphylaxis,  urticaria,  and  angioedema  frequently  share  a  common  pathophysiology  in  that  these  conditions  most  commonly  result  from  immunoglobulin  E  (IgE)-mediated  mast  cell  activation,  resulting  in  the  release  of  histamine,  leukotrienes,  and  other  mast  cell  mediators.  Urticaria  and  angioedema  are  isolated  to  mucocutaneous  symptoms,  whereas  anaphylaxis  is  an  acute  systemic  reaction  that  may  rapidly  lead  to  cardiopulmonary  collapse.