RT Book, Section A1 Davis, Carla M. A1 Garcia-Lloret, Maria A2 Kline, Mark W. SR Print(0) ID 1182931894 T1 Food Allergy T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182931894 RD 2024/04/20 AB Food allergies, defined as adverse immune responses to food proteins, are an increasingly common concern in pediatrics. Food allergy is very distinct from food intolerance, which is defined as a nonimmune reaction that includes metabolic, toxic, pharmacologic, and undefined mechanisms. Food allergy is not one disease but a spectrum of clinicopathologic disorders. As such, manifestations of food allergies differ significantly, depending on the immune mechanism involved and the affected target organ, and range from the prototypical symptoms of acute urticaria/angioedema to chronic conditions such as eczema or eosinophilic gastrointestinal disease. The severity of a food allergic reaction may vary with similar exposures and even in the same individual. As a whole, fatalities are rare, but they do occur. Teenagers are particularly vulnerable because they are risk takers and, therefore, may ignore warning signs of an impending severe reaction.