RT Book, Section
A1 Zulian, Francesco
A2 Kline, Mark W.
SR Print(0)
ID 1182932530
T1 Juvenile Scleroderma
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182932530
RD 2023/04/02
AB Juvenile  scleroderma  syndromes  are  multisystem  autoimmune  rheumatic  diseases  for  which  the  unifying  characteristic  is  the  development  of  hard  skin  before  age  16.  They  can  be  separated  into  2  main  categories:  1)  juvenile  systemic  sclerosis  (JSSc),  characterized  by  diffuse  skin  sclerosis  involving  many  sites  of  the  body  together  with  internal  organ  involvement,  and  2)  juvenile  localized  scleroderma  (JLS),  characterized  by  circumscribed  skin  induration  but  no  vascular  or  internal  organ  involvement.