RT Book, Section
A1 Nelson, Marie V.
A1 Dome, Jeffrey S.
A2 Kline, Mark W.
SR Print(0)
ID 1182911445
T1 Renal Tumors
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182911445
RD 2024/04/18
AB Renal  tumors  account  for  approximately  7%  of  all  childhood  cancers.  While  80%  of  these  are  Wilms  tumors  (or  nephroblastomas),  other  kidney  tumors  of  childhood  include  renal  cell  carcinoma  (~4%),  clear  cell  sarcoma  of  the  kidney  (~3%),  congenital  mesoblastic  nephroma  (~2%),  rhabdoid  tumor  of  the  kidney  (~2%),  and  cystic  nephroma  (~2%).  Wilms  tumor  (WT)  is  the  second  most  common  extracranial  solid  tumor  in  pediatrics,  following  neuroblastoma.  While  overall  survival  in  patients  with  WT  has  increased  to  90%  due  to  advances  in  medical  and  surgical  treatment,  there  remain  subsets  of  patients  who  do  not  have  favorable  outcomes.  Moreover,  patients  with  renal  cell  carcinoma,  clear  cell  carcinoma,  and  rhabdoid  tumor  of  the  kidney  have  considerably  worse  outcomes  compared  to  WT.  This  chapter  will  focus  primarily  on  WT  as  the  most  prevalent  pediatric  kidney  tumor.