RT Book, Section
A1 Tomlinson, Gail E.
A1 Katzenstein, Howard M.
A2 Kline, Mark W.
SR Print(0)
ID 1182911529
T1 Malignant Liver Tumors
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182911529
RD 2024/10/04
AB Liver  tumors  represent  approximately  1%  of  all  childhood  cancers.  There  are  approximately  100  to  150  new  cases  of  liver  cancer  diagnosed  in  children  each  year  in  the  United  States.  Hepatoblastoma,  the  most  common  malignant  tumor  of  the  liver,  accounts  for  two-thirds  of  all  liver  cancer  in  children.  Hepatoblastoma  typically  occurs  in  the  very  young  child,  with  a  mean  age  of  onset  between  18  to  20  months  and  95%  of  cases  occurring  before  5  years  of  age.  The  incidence  of  hepatoblastoma  has  approximately  doubled  over  the  past  few  decades.  Hepatoblastoma  is  considered  an  embryonal  tumor  because,  histologically,  tumor  cells  resemble  cells  seen  in  the  developing  liver.