RT Book, Section A1 Dvorak, Christopher C. A1 Auletta, Jeffery J. A2 Kline, Mark W. SR Print(0) ID 1182933719 T1 Fever and Infection in the Immunocompromised Patient T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182933719 RD 2024/04/25 AB A key element in the effective care of immunocompromised patients with fever is hypervigilance. Not only are these patients at increased risk for a diverse range of microorganisms, but also infections caused by these organisms can present in subtle or atypical ways and often progress to difficult-to-treat chronic disease states or rapid clinical decompensation. Therefore, empiric anti-infective therapy is justified for new-onset fever in immunocompromised patients while a thorough investigation into the source of fever is performed. Because antimicrobial therapies often have adverse side effects, an accurate evaluation to guide definitive antimicrobial therapy becomes crucial.