RT Book, Section A1 Telega, Grzegorz A2 Kline, Mark W. SR Print(0) ID 1182934425 T1 Infections of the Liver T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182934425 RD 2024/03/28 AB Patients with infections of the liver generally present with nonspecific symptoms such as fever, fatigue, abdominal pain, or weight loss. The abdominal pain may be diffuse, be confined to the right upper quadrant, or radiate to the shoulder or back. Other symptoms may include headache, arthralgias, and adenopathy. The initial history should focus on geographic location or travel, unprotected sex or drug use, use of hemodialysis or blood products, other recent exposures, vaccination/immune status, chronicity of symptoms, anatomical anomalies or surgery that may affect the biliary tracts, and family history of hepatitis. Physical exam is often normal; some patients will have right upper quadrant or diffuse abdominal tenderness and hepatomegaly. Jaundice or stigmata of chronic liver disease is infrequent. For additional details regarding viral hepatitis, please refer to Table 232-1 and Chapter 303.