RT Book, Section
A1 Acker, Karen P.
A1 Saiman, Lisa
A2 Kline, Mark W.
SR Print(0)
ID 1182935492
T1 Pseudomonas, Burkholderia, and Stenotrophomonas
T2 Rudolph's Pediatrics, 23e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259588594
LK accesspediatrics.mhmedical.com/content.aspx?aid=1182935492
RD 2024/04/19
AB Pseudomonas,  Burkholderia,  and  Stenotrophomonas  species  are  non–lactose-fermenting  gram-negative  bacilli  that  are  frequently  multidrug  resistant  and  are  important  pathogens,  particularly  in  healthcare-associated  infections  in  immunocompromised  patients  and  in  individuals  with  cystic  fibrosis  (CF).  Previously,  Burkholderia  and  Stenotrophomonas  species  were  classified  as  Pseudomonas  due  to  their  similar  biochemical  properties.  In  1992,  the  genus  Burkholderia  was  proposed  for  7  species.  There  has  been  a  rapid  increase  in  newly  identified  species  to  >  70  species  that  are  very  similar  phenotypically,  thus  making  taxonomic  classification  somewhat  perplexing  without  the  use  of  molecular  strategies.  The  most  commonly  identified  species  within  the  Burkholderia  cepacia  complex  are  Burkholderia  cenocepacia  and  Burkholderia  multivorans.  Stenotrophomonas  was  initially  reclassified  as  Xanthomonas  in  1983  and  acquired  its  present  classification  in  1993.  Stenotrophomonas  maltophilia  is  the  only  species  within  its  genus  known  to  cause  human  disease.