RT Book, Section A1 Honegger, Jonathan A1 Watson, Joshua R. A2 Kline, Mark W. SR Print(0) ID 1182903554 T1 Human Immunodeficiency Virus Type 1 Infection T2 Rudolph's Pediatrics, 23e YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9781259588594 LK accesspediatrics.mhmedical.com/content.aspx?aid=1182903554 RD 2024/04/24 AB Approximately 2.1 million children younger than age 15 years were living with human immunodeficiency virus type 1 (HIV-1) infection in 2016, including 160,000 newly infected children. In the same year, nearly 120,000 children died from acquired immunodeficiency syndrome (AIDS)-related illnesses, and hundreds of thousands more children lost one or both parents to HIV. HIV clearly continues to exert a devastating effect on global child health. Nevertheless, expanded access to antiretroviral therapy (ART) is turning the tide of this epidemic. The numbers of children newly infected with HIV-1 and children dying of AIDS-related illness in 2016 were approximately half what they were in 2010. For many children with access to ART, HIV-1 has become a manageable, chronic disease rather a certain cause of early death.